THO Complex 3 antibody (Middle Region)

Catalog No. ABIN2776596

Product Details anti-THO Complex 3 Antibody

Target: THO Complex 3 (THOC3)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THO Complex 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PDGQTIAVGN KDDVVTFIDA KTHRSKAEEQ FKFEVNEISW NNDNNMFFLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against THOC3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THOC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 351 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-THO Complex 3 antibody (ABIN2776596)

Strässer, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez-Navarro, Rondón, Aguilera, Struhl, Reed, Hurt: "TREX is a conserved complex coupling transcription with messenger RNA export." in: Nature, Vol. 417, Issue 6886, pp. 304-8, (2002) (PubMed).

Target Details for THO Complex 3

Target: THO Complex 3 (THOC3)

Alternative Name: THOC3 (THOC3 Products)

Synonyms: THOC3 antibody, zgc:100815 antibody, THO3 antibody, hTREX45 antibody, 2410044K02Rik antibody, AL033344 antibody, THO complex 3 antibody, THO complex subunit 3 antibody, THOC3 antibody, thoc3 antibody, LOC100400596 antibody, Thoc3 antibody

Background: THOC3 is part of the TREX (transcription/export) complex, which includes THO2, HPR1, ALY, and UAP56.TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM].
Alias Symbols: TEX1
Protein Interaction Partner: THOC2, ALYREF, THOC5, DDX39B, SUMO2, NCBP1, UBC, MLKL, BRCA1, ZCRB1, THOC7, THOC6, ZC3H15, ZKSCAN5, THOC1, VIM, UTRN, TTC1, HDGF, TK1, YOD1,
Protein Size: 351

Molecular Weight: 39 kDa

Gene ID: 84321

NCBI Accession: NM_032361, NP_115737

UniProt: Q96J01