SLIRP antibody (N-Term)

Catalog No. ABIN2776583

Product Details anti-SLIRP Antibody

Target: SLIRP (SRA Stem-Loop Interacting RNA Binding Protein (SLIRP))

Binding Specificity: N-Term

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLIRP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PFDKETGFHR GLGWVQFSSE EGLRNALQQE NHIIDGVKVQ VHTRRPKLPQ

Predicted Reactivity: Cow: 86%, Dog: 79%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 86%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against C14ORF156. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C14ORF156

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 109 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLIRP

Target: SLIRP (SRA Stem-Loop Interacting RNA Binding Protein (SLIRP))

Alternative Name: C14ORF156 (SLIRP Products)

Synonyms: C14orf156 antibody, SLIRP antibody, DKFZp468C196 antibody, DC50 antibody, PD04872 antibody, 1810035L17Rik antibody, C10H14orf156 antibody, SRA stem-loop interacting RNA binding protein antibody, Slirp antibody, C14orf156 antibody, SLIRP antibody

Background: As a RNA-binding protein, C14orf156 acts as a nuclear receptor corepressor. It probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. C14orf156 binds the STR7 loop of SRA RNA. It is also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.
Alias Symbols: DC50, PD04872, C14orf156
Protein Interaction Partner: KRT40, CCDC102B, MTUS2, PNMA1, HAUS2, VCP, UBC, MDM2, ASB5, ADRB2, vpu, CSNK2A1, SCAMP3, RBM8A, MRRF, SUGP1, SBDS, U2AF2, DSTN, SF3B4, HNRNPR, PPIF, SNRPC, SNRNP70, RPL38, RFX5, PIN4, ILF3, HNRNPA2B1, ELAVL1, EIF4G2, PQBP1, ICT1, SLX1B, BABAM1,
Protein Size: 109

Molecular Weight: 12 kDa

Gene ID: 81892

NCBI Accession: NM_031210, NP_112487

UniProt: Q9GZT3