EIF4H antibody (Middle Region)

Catalog No. ABIN2776554

Product Details anti-EIF4H Antibody

Target: EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DSRDDFNSGF RDDFLGGRGG SRPGDRRTGP PMGSRFRDGP PLRGSNMDFR

Predicted Reactivity: Dog: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against WBSCR1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WBSCR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF4H

Target: EIF4H (Eukaryotic Translation Initiation Factor 4H (EIF4H))

Alternative Name: WBSCR1 (EIF4H Products)

Background: WBSCR1 is one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization.This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
Alias Symbols: WSCR1, WBSCR1, eIF-4H
Protein Interaction Partner: LNX1, C11orf68, UBC, GINS2, MAT2B, AHSA1, NDRG1, RPS6KA1, PGD, GLA, G6PD, EIF5, EEF2, CASP7, FN1, MRPL44, MRPL9, PUF60, NUDT21, HNRNPA0, SYNCRIP, HNRNPDL, EIF3A, TRA2B, SRSF3, RBMS2, ICT1, EIF4G2, EIF4E, EIF4A1, DGKQ, AI837181,
Protein Size: 248

Molecular Weight: 27 kDa

Gene ID: 7458

NCBI Accession: NM_022170, NP_071496

UniProt: Q15056

Pathways: SARS-CoV-2 Protein Interactome