MLXIP antibody (Middle Region)

Catalog No. ABIN2776519

Product Details anti-MLXIP Antibody

Target: MLXIP (MLX Interacting Protein (MLXIP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DEQGCEHTSR TEDPFIQPTD FGPSEPPLSV PQPFLPVFTM PLLSPSPAPP

Predicted Reactivity: Dog: 100%, Human: 100%, Mouse: 79%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against MLXIP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MLXIP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 919 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MLXIP antibody (ABIN2776519)

Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: "Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6912-7, (2008) (PubMed).

Target Details for MLXIP

Target: MLXIP (MLX Interacting Protein (MLXIP))

Alternative Name: MLXIP (MLXIP Products)

Synonyms: MGC83884 antibody, si:ch211-110p13.4 antibody, MIR antibody, MONDOA antibody, bHLHe36 antibody, AW228700 antibody, B930074I24 antibody, Mir antibody, mKIAA0867 antibody, RGD1560774 antibody, MLX interacting protein antibody, MLX interacting protein L homeolog antibody, MLXIP antibody, mlxip.L antibody, mlxip antibody, Mlxip antibody

Background: MONDOA forms heterodimers with MLX (MIM 602976) that can bind to and activate transcription from CACGTG E boxes.
Alias Symbols: KIAA0867, MIR, MONDOA, bHLHe36
Protein Interaction Partner: CNPY2, MLX, YWHAB,
Protein Size: 919

Molecular Weight: 101 kDa

Gene ID: 22877

NCBI Accession: NM_014938, NP_055753

UniProt: Q9HAP2