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POLR2I antibody (N-Term)

POLR2I Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776452
  • Target See all POLR2I Antibodies
    POLR2I (Polymerase (RNA) II (DNA Directed) Polypeptide I, 14.5kDa (POLR2I))
    Binding Specificity
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 22
    • 13
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Saccharomyces cerevisiae
    Host
    • 20
    • 2
    Rabbit
    Clonality
    • 20
    • 2
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This POLR2I antibody is un-conjugated
    Application
    • 10
    • 9
    • 2
    Western Blotting (WB)
    Sequence
    ACRNCDYQQE ADNSCIYVNK ITHEVDELTQ IIADVSQDPT LPRTEDHPCQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against POLR2I. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human POLR2I
    Top Product
    Discover our top product POLR2I Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 125 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    POLR2I (Polymerase (RNA) II (DNA Directed) Polypeptide I, 14.5kDa (POLR2I))
    Alternative Name
    POLR2I (POLR2I Products)
    Synonyms
    RPB9 antibody, hRPB14.5 antibody, GB18029 antibody, RPB14.5 antibody, 2810002B19Rik antibody, zgc:103515 antibody, RNA polymerase II subunit I antibody, DNA-directed RNA polymerase II subunit RPB9 antibody, DNA-directed RNA polymerase II 14.5 kDa polypeptide antibody, polymerase (RNA) II (DNA directed) polypeptide I antibody, polymerase (RNA) II subunit I L homeolog antibody, POLR2I antibody, LOC412547 antibody, LOC100282092 antibody, Polr2i antibody, polr2i antibody, polr2i.L antibody
    Background
    POLR2I is a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. POLR2I has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: RPB9, hRPB14.5
    Protein Interaction Partner: ESR1, TCEB3, SRC, PSMB9, UBC, MED19, MED26, RECQL5, TBCD, BRCA1, CPSF6, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, DCUN1D1, CUL5, MYC, tat, WDR48, POLR2H, MED10, MED29,
    Protein Size: 125
    Molecular Weight
    14 kDa
    Gene ID
    5438
    NCBI Accession
    NM_006233, NP_006224
    UniProt
    P36954
    Pathways
    Regulatory RNA Pathways
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