ONECUT2 antibody (Middle Region)

Catalog No. ABIN2776431

Product Details anti-ONECUT2 Antibody

Target: ONECUT2 (One Cut Homeobox 2 (ONECUT2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Guinea Pig, Rat, Dog, Rabbit, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ONECUT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NGLHHPGHTQ SHGPVLAPSR ERPPSSSSGS QVATSGQLEE INTKEVAQRI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ONECUT2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ONECUT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 485 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ONECUT2

Target: ONECUT2 (One Cut Homeobox 2 (ONECUT2))

Alternative Name: ONECUT2 (ONECUT2 Products)

Synonyms: C730009D12 antibody, OC-2 antibody, Oc2 antibody, OC2 antibody, RGD1564677 antibody, one cut domain, family member 2 antibody, one cut homeobox 2 antibody, Onecut2 antibody, ONECUT2 antibody

Background: ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism.
Alias Symbols: OC2, OC-2
Protein Interaction Partner: KDM5B,
Protein Size: 485

Molecular Weight: 52 kDa

Gene ID: 9480

NCBI Accession: NM_004852, NP_004843

UniProt: O95948