NMI antibody (Middle Region)

Catalog No. ABIN2776425

Product Details anti-NMI Antibody

Target: NMI (N-Myc (And STAT) Interactor (NMI))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SFSKSRNGGG EVDRVDYDRQ SGSAVITFVE IGVADKILKK KEYPLYINQT

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against NMI. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NMI

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 307 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NMI

Target: NMI (N-Myc (And STAT) Interactor (NMI))

Alternative Name: NMI (NMI Products)

Synonyms: fj02e01 antibody, wu:fj02e01 antibody, NMI antibody, MGC108489 antibody, N-myc and STAT interactor antibody, N-myc (and STAT) interactor antibody, N-myc and STAT interactor L homeolog antibody, NMI antibody, Nmi antibody, nmi antibody, nmi.L antibody

Background: NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has high expression in myeloid leukemia cell lines. NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: HSPA8, GCSH, GOLGA8EP, HDDC3, C9orf72, TXLNA, TXLNB, CNKSR3, LCA5L, C1orf216, SFR1, TUBA3E, MTMR9, COPS7B, BRMS1, KDM1A, POMZP3, HHLA3, EMILIN1, SNAPC5, MAD2L1BP, NMI, MTMR6, SCEL, TRAF5, UBC, PSMG3, OXR1, EXOSC4, TOLLIP, CYHR1, VPS26A, H1FX, NAA10, TBCD,
Protein Size: 307

Molecular Weight: 35 kDa

Gene ID: 9111

NCBI Accession: NM_004688, NP_004679

UniProt: Q13287