MED21 antibody (N-Term)

Catalog No. ABIN2776418

Product Details anti-MED21 Antibody

Target: MED21 (Mediator Complex Subunit 21 (MED21))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED21 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Sequence: FCNAIGVLQQ CGPPASFSNI QTAINKDQPA NPTEEYAQLF AALIARTAKD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Med21. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 144 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MED21

Target: MED21 (Mediator Complex Subunit 21 (MED21))

Alternative Name: Med21 (MED21 Products)

Synonyms: SURB7 antibody, fk48d02 antibody, surb7 antibody, wu:fk48d02 antibody, zgc:56532 antibody, SRB7 antibody, hSrb7 antibody, 0610007L03Rik antibody, AI449604 antibody, D19234 antibody, D6Ertd782e antibody, Srb7 antibody, Surb7 antibody, T4B21.8 antibody, T4B21_8 antibody, mediator 21 antibody, mediator complex subunit 21 antibody, Med21p antibody, mediator 21 antibody, MED21 antibody, med21 antibody, Med21 antibody

Background: Med21 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: 0610007L03Rik, AI449604, D19234, D6Ertd782e, Srb7, Surb7
Protein Interaction Partner: Med21, Med6, Aagab, Med7, Mcrs1, Pik3ca, Ltb, Brd2, Nfe2,
Protein Size: 144

Molecular Weight: 15 kDa

Gene ID: 108098

NCBI Accession: NM_025315, NP_079591

UniProt: Q9CQ39

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha