HTR3E antibody (Middle Region)

Catalog No. ABIN2776341

Product Details anti-HTR3E Antibody

Target: HTR3E (Serotonin Receptor 3E (HTR3E))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HTR3E antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: RWLHSLLLHC NSPGRCCPTA PQKENKGPGL TPTHLPGVKE PEVSAGQMPG

Predicted Reactivity: Dog: 100%, Horse: 83%, Human: 100%, Rabbit: 83%

Characteristics: This is a rabbit polyclonal antibody against HTR3E. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HTR3E

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HTR3E

Target: HTR3E (Serotonin Receptor 3E (HTR3E))

Alternative Name: HTR3E (HTR3E Products)

Synonyms: 5-HT3-E antibody, 5-HT3E antibody, 5-HT3c1 antibody, 5-hydroxytryptamine receptor 3E antibody, HTR3E antibody

Background: HTR3E belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
Alias Symbols: 5-HT3c1, MGC120035, MGC120036, MGC120037, 5-HT3E, 5-HT3-E
Protein Size: 471

Molecular Weight: 53 kDa

Gene ID: 285242

NCBI Accession: NM_182589, NP_872395

UniProt: A5X5Y0