KCNIP2 antibody (N-Term)

Catalog No. ABIN2776321

Product Details anti-KCNIP2 Antibody

Target: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Cow, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALAAPASLRP HRPRLLDPDS VDDEFELSTV CHRPEGLEQL QEQTKFTRKE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against KCNIP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNIP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 285 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNIP2

Target: KCNIP2 (Kv Channel Interacting Protein 2 (KCNIP2))

Alternative Name: KCNIP2 (KCNIP2 Products)

Synonyms: KCHIP2 antibody, KCNIP2 antibody, Kchip2 antibody, KChIP2 antibody, kchip2 antibody, si:ch73-173h19.2 antibody, potassium voltage-gated channel interacting protein 2 antibody, Kv channel-interacting protein 2 antibody, Kv channel interacting protein 2 S homeolog antibody, Kv channel interacting protein 2 antibody, KCNIP2 antibody, Kcnip2 antibody, kcnip2.S antibody, kcnip2 antibody

Background: KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
Alias Symbols: DKFZp566L1246, KCHIP2, MGC17241
Protein Interaction Partner: KCND2, KCNIP1, KCNIP2, KCNE4, KCND3, KCNIP4,
Protein Size: 285

Molecular Weight: 32 kDa

Gene ID: 30819

NCBI Accession: NM_014591, NP_055406