KCTD12 antibody (C-Term)

Catalog No. ABIN2776278

Product Details anti-KCTD12 Antibody

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCTD12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PDRPPERYTS RYYLKFNFLE QAFDKLSESG FHMVACSSTG TCAFASSTDQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Kctd12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of MOUSE Kctd12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCTD12

Target: KCTD12 (Potassium Channel Tetramerisation Domain Containing 12 (KCTD12))

Alternative Name: Kctd12 (KCTD12 Products)

Background: Kctd12 is an auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. It increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Alias Symbols: AU046135, AW538430, Pfet1, Pfetin
Protein Size: 327

Molecular Weight: 35 kDa

Gene ID: 239217

NCBI Accession: NM_177715, NP_808383

UniProt: Q6WVG3

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling