Kir2.2 antibody (Middle Region)
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- Target See all Kir2.2 (KCNJ12) Antibodies
- Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Dog, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Kir2.2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KDLVENKFLL PSANSFCYEN ELAFLSRDEE DEADGDQDGR SRDGLSPQAR
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against KCNJ12. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KCNJ12
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 433 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))
- Alternative Name
- KCNJ12 (KCNJ12 Products)
- Synonyms
- IRK-2 antibody, IRK2 antibody, KCNJN1 antibody, Kir2.2 antibody, Kir2.2v antibody, hIRK antibody, hIRK1 antibody, hkir2.2x antibody, kcnj12x antibody, Kir2.1 antibody, IRK antibody, KIR2.2 antibody, MB-IRK2 antibody, potassium voltage-gated channel subfamily J member 12 antibody, ATP-sensitive inward rectifier potassium channel 12 antibody, potassium inwardly-rectifying channel, subfamily J, member 12 antibody, KCNJ12 antibody, LOC746628 antibody, Kcnj12 antibody
- Background
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KCNJ12 is an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). This gene is located within the Smith-Magenis syndrome region on chromosome 17. This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-486 BC027982.1 12-497 487-488 AC068418.5 101651-101652 489-2455 BC027982.1 500-2466 2456-2483 DA115102.1 132-159 2484-2485 AC068418.5 141899-141900 2486-2889 DA115102.1 161-564 2890-3454 BM799671.1 118-682 3455-3457 AC068418.5 142870-142872 3458-4692 AK024229.1 926-2160 4693-5230 AK024229.1 2163-2700
Alias Symbols: FLJ14167, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x, IRK-2
Protein Interaction Partner: UBC, LIN7C, LIN7B, DLG2, LIN7A, DLG4, APBA1, ABLIM1, PRKACA, DTNA, SNTA1, DLG1, SNTB2, SNTB1, DMD, DLG3, CASK, MPP6,
Protein Size: 433 - Molecular Weight
- 49 kDa
- Gene ID
- 3768
- NCBI Accession
- NM_021012, NP_066292
- UniProt
- Q14500
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