MLC1 antibody (Middle Region)

Catalog No. ABIN2776210

Product Details anti-MLC1 Antibody

Target: MLC1

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SDSANILDEV PFPARVLKSY SVVEVIAGIS AVLGGIIALN VDDSVSGPHL

Predicted Reactivity: Cow: 91%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 83%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MLC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MLC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 377 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MLC1

Target: MLC1

Abstract: MLC1 Products

Synonyms: LVM antibody, MLC antibody, VL antibody, AW048630 antibody, BB074274 antibody, Kiaa0027-hp antibody, WKL1 antibody, mKIAA0027 antibody, si:ch211-192n14.1 antibody, megalencephalic leukoencephalopathy with subcortical cysts 1 antibody, megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) antibody, MLC1 antibody, Mlc1 antibody, mlc1 antibody

Background: MLC1 may be a transporter. It may act as a non-selective neuronal cation channel.The function of this gene product is unknown, however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: KIAA0027, LVM, MLC, VL
Protein Interaction Partner: KDM1A, PRMT6, Cav2, Dtnb, Snta1, Dtna, Tuba1a, Kcnj10, Cav1, UBC, TPT1, DAPK2, MYLK,
Protein Size: 377

Molecular Weight: 41 kDa

Gene ID: 23209

NCBI Accession: NM_015166, NP_055981

UniProt: Q15049