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MLC1 antibody (Middle Region)

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2776210
  • Target See all MLC1 products
    MLC1
    Binding Specificity
    • 15
    • 14
    • 8
    • 5
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig
    Host
    • 37
    • 1
    Rabbit
    Clonality
    • 38
    Polyclonal
    Conjugate
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MLC1 antibody is un-conjugated
    Application
    • 32
    • 20
    • 13
    • 13
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SDSANILDEV PFPARVLKSY SVVEVIAGIS AVLGGIIALN VDDSVSGPHL
    Predicted Reactivity
    Cow: 91%, Dog: 86%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 83%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against MLC1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human MLC1
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 377 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MLC1
    Abstract
    MLC1 Products
    Synonyms
    LVM antibody, MLC antibody, VL antibody, AW048630 antibody, BB074274 antibody, Kiaa0027-hp antibody, WKL1 antibody, mKIAA0027 antibody, si:ch211-192n14.1 antibody, megalencephalic leukoencephalopathy with subcortical cysts 1 antibody, megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human) antibody, MLC1 antibody, Mlc1 antibody, mlc1 antibody
    Background
    MLC1 may be a transporter. It may act as a non-selective neuronal cation channel.The function of this gene product is unknown, however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alias Symbols: KIAA0027, LVM, MLC, VL
    Protein Interaction Partner: KDM1A, PRMT6, Cav2, Dtnb, Snta1, Dtna, Tuba1a, Kcnj10, Cav1, UBC, TPT1, DAPK2, MYLK,
    Protein Size: 377
    Molecular Weight
    41 kDa
    Gene ID
    23209
    NCBI Accession
    NM_015166, NP_055981
    UniProt
    Q15049
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