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SCN8A antibody (C-Term)
SCN8A
Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-SCN8A Antibody
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Target
See all SCN8A Antibodies
SCN8A
(Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
Binding Specificity
All epitopes for SCN8A antibodies
C-Term
Reactivity
All reactivities for SCN8A antibodies
Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Pig
Host
All hosts for SCN8A antibodies
Rabbit
Clonality
All clonalities for SCN8A antibodies
Polyclonal
Conjugate
All conjugates for SCN8A antibodies
This SCN8A antibody is un-conjugated
Application
All applications for SCN8A antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Sequence
KSSIFSFRGP GRFRDPGSEN EFADDEHSTV EESEGRRDSL FIPIRARERR
Predicted Reactivity
Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Characteristics
This is a rabbit polyclonal antibody against SCN8A. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of human SCN8A
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Discover our top product SCN8A Primary Antibody
Alternatives
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anti-Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A) (AA 1116-1165) antibody
SCN8A
Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Monkey, Pig, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
anti-Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A) (Middle Region) antibody
SCN8A
Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for SCN8A
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Target
SCN8A
(Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))
Alternative Name
SCN8A (SCN8A Products )
Synonyms
CERIII antibody, CIAT antibody, EIEE13 antibody, MED antibody, NaCh6 antibody, Nav1.6 antibody, PN4 antibody, AI853486 antibody, C630029C19Rik antibody, dmu antibody, med antibody, mnd-2 antibody, mnd2 antibody, nmf2 antibody, nmf335 antibody, nmf58 antibody, nur14 antibody, seal antibody, sodium voltage-gated channel alpha subunit 8 antibody, sodium channel, voltage-gated, type VIII, alpha antibody, SCN8A antibody, Scn8a antibody
Background
This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants. Alias Symbols: MED, PN4, CIAT, NaCh6, CERIII, EIEE13, Nav1.6 Protein Size: 475
Molecular Weight
52 kDa
Gene ID
6334
NCBI Accession
NM_001177984 , NP_001171455
UniProt
Q9UQD0
Pathways
Sensory Perception of Sound
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