KCNJ4 antibody (Middle Region)
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- Target See all KCNJ4 Antibodies
- KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNJ4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AVAAGLGLEA GSKEEAGIIR MLEFGSHLDL ERMQASLPLD NISYRRESAI
- Predicted Reactivity
- Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against KCNJ4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human KCNJ4
- Top Product
- Discover our top product KCNJ4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 445 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KCNJ4 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 4 (KCNJ4))
- Alternative Name
- KCNJ4 (KCNJ4 Products)
- Synonyms
- KCNJ4 antibody, CKIR2.3 antibody, HIR antibody, HIRK2 antibody, HRK1 antibody, IRK-3 antibody, IRK3 antibody, Kir2.3 antibody, Kcnf2 antibody, MB-IRK3 antibody, Hirk2 antibody, potassium voltage-gated channel subfamily J member 4 antibody, potassium inwardly-rectifying channel, subfamily J, member 4 antibody, KCNJ4 antibody, Kcnj4 antibody
- Background
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KCNJ4 is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have??een found for this gene. Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neuronsSeveral different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: HIR, HIRK2, HRK1, IRK3, Kir2.3, MGC142066, MGC142068, IRK-3
Protein Interaction Partner: SNTA1, LIN7B, GNGT2, DLG2, IL16, DLG4, DLG1, KCNJ2, CASK, PRKCD, LIN7C, LIN7A, DMD,
Protein Size: 445 - Molecular Weight
- 49 kDa
- Gene ID
- 3761
- NCBI Accession
- NM_004981, NP_004972
- UniProt
- P48050
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