P2RX1 antibody (Middle Region)
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- Target See all P2RX1 Antibodies
- P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Rabbit, Dog, Cow, Horse, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This P2RX1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- VVGITIDWHC DLDWHVRHCR PIYEFHGLYE EKNLSPGFNF RFARHFVENG
- Predicted Reactivity
- Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against P2RX1. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human P2RX1
- Top Product
- Discover our top product P2RX1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 399 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- P2RX1 (Purinergic Receptor P2X, Ligand Gated Ion Channel 1 (P2RX1))
- Alternative Name
- P2RX1 (P2RX1 Products)
- Synonyms
- p2xr1 antibody, P2X1 antibody, AI323649 antibody, BB122383 antibody, P2x antibody, Pdcd3 antibody, RP-2 antibody, P2XMR antibody, P2X1R antibody, purinergic receptor P2X, ligand-gated ion channel, 1 antibody, purinergic receptor P2X 1 antibody, calcium/calmodulin dependent protein kinase kinase 1 antibody, p2rx1 antibody, P2RX1 antibody, P2rx1 antibody, CAMKK1 antibody
- Background
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P2RX1 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Alias Symbols: P2X1
Protein Interaction Partner: P2RX2,
Protein Size: 399 - Molecular Weight
- 45 kDa
- Gene ID
- 5023
- NCBI Accession
- NM_002558, NP_002549
- UniProt
- P51575
- Pathways
- Positive Regulation of Endopeptidase Activity
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