GABRR2 antibody (Middle Region)
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- Target See all GABRR2 Antibodies
- GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GABRR2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- SNKSMTFDGR LVKKIWVPDV FFVHSKRSFT HDTTTDNIML RVFPDGHVLY
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against GABRR2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GABRR2
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 490 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway." in: Translational psychiatry, Vol. 3, pp. e271, (2013) (PubMed).
: "
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mRNA and protein expression for novel GABAA receptors ? and ?2 are altered in schizophrenia and mood disorders; relevance to FMRP-mGluR5 signaling pathway." in: Translational psychiatry, Vol. 3, pp. e271, (2013) (PubMed).
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- Target
- GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))
- Alternative Name
- GABRR2 (GABRR2 Products)
- Synonyms
- si:dkey-181i3.1 antibody, gamma-aminobutyric acid type A receptor rho2 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, rho 2b antibody, gamma-aminobutyric acid type A receptor rho 2 subunit antibody, gamma-aminobutyric acid (GABA) C receptor, subunit rho 2 antibody, gamma-aminobutyric acid receptor subunit rho-2 antibody, GABRR2 antibody, gabrr2b antibody, Gabrr2 antibody, LOC100653501 antibody
- Background
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GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR2 is a member of the rho subunit family and is a component of the GABA receptor complex.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-30 BX490975.1 60-89 31-1586 BC130352.1 1-1556 1587-1631 M86868.1 1584-1628
Alias Symbols: -
Protein Interaction Partner: GABRR1, SQSTM1, PRKCA, MAP1B, CSNK2A1,
Protein Size: 490 - Molecular Weight
- 54 kDa
- Gene ID
- 2570
- NCBI Accession
- NM_002043, NP_002034
- UniProt
- P28476
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