CLIC1 antibody (N-Term)

Catalog No. ABIN2776130

Product Details anti-CLIC1 Antibody

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Horse, Goat, Rabbit, Guinea Pig, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GQLPFLLYGT EVHTDTNKIE EFLEAVLCPP RYPKLAALNP ESNTAGLDIF

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CLIon Channel1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLIC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 241 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CLIC1 antibody (ABIN2776130)

Yang, Jung, Cho, Choi, Kim, Kim, Kim, Jang, Lee, Han, Shin: "Chloride intracellular channel 1 regulates osteoblast differentiation." in: Bone, Vol. 45, Issue 6, pp. 1175-85, (2009) (PubMed).

Target Details for CLIC1

Target: CLIC1 (Chloride Intracellular Channel 1 (CLIC1))

Alternative Name: CLIC1 (CLIC1 Products)

Synonyms: ncc27 antibody, xclic1 antibody, MGC75951 antibody, MGC132377 antibody, CLIC1 antibody, G6 antibody, NCC27 antibody, Clcp antibody, wu:fc30e04 antibody, zgc:77044 antibody, chloride intracellular channel 1 antibody, chloride intracellular channel 1 S homeolog antibody, clic1 antibody, CLIC1 antibody, Clic1 antibody, clic1.S antibody

Background: Chloride intracellular channel 1 is a member of the p64 family, a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH , and regulation of cell volume. CLIon Channel1 encodes a protein that localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
Alias Symbols: G6, NCC27
Protein Interaction Partner: UBC, PSMD10, SUMO2, SUMO1, NEDD8, FBXO6, ZNF302, NUP62, PRDX4, IKBKG, ZNF184, VCAM1, THRA, RPLP1, NTF4, ITGA4, FN1, ATF2, CPT1A, ATP6V0A1, ATP6V0C, ATP5F1, ALOX5AP, GRK5, MYOC, CDK2, ISG15, ARRB2, SUMO4, LSM1, AKAP9, TRAPPC2,
Protein Size: 241

Molecular Weight: 27 kDa

Gene ID: 1192

NCBI Accession: NM_001288, NP_001279

UniProt: Q502X1