NMDAR2A antibody (Middle Region)
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- Target See all NMDAR2A (GRIN2A) Antibodies
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NMDAR2A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- DKIYTIDGEK EPGFHLDPPQ FVENVTLPEN VDFPDPYQDP SENFRKGDST
- Predicted Reactivity
- Cow: 77%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against GRIN2A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GRIN2A
- Top Product
- Discover our top product GRIN2A Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1464 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
- Alternative Name
- GRIN2A (GRIN2A Products)
- Synonyms
- NMDAR2A antibody, nr2a antibody, GRIN2A antibody, EPND antibody, GluN2A antibody, NR2A antibody, glutamate ionotropic receptor NMDA type subunit 2A antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antibody, glutamate receptor ionotropic, NMDA 2A antibody, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antibody, GRIN2A antibody, grin2a.L antibody, LOC100438553 antibody, Grin2a antibody
- Background
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N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D).N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NMDAR2A, NR2A, EPND, GluN2A
Protein Interaction Partner: Nedd4, SPTAN1, DLG4, DLG1, UBC, GRIN1, ARHGAP32, CAMK2B, GRIN3B, GRIN3A, DLGAP1, CAMK2A, DLG2, AP1M1, INADL, IL16, AP4M1, RGS3, PTK2B, DLG3, CASK, SRC, PRKCA, PTPN4, PLCG1, GRIN2A, FYN, CDK5, ACTN1, Dlgap2,
Protein Size: 1464 - Molecular Weight
- 163 kDa
- Gene ID
- 2903
- NCBI Accession
- NM_000833, NP_000824
- UniProt
- Q12879
- Pathways
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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