DIDO1 antibody (N-Term)
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- Target See all DIDO1 Antibodies
- DIDO1 (Death Inducer-Obliterator 1 (DIDO1))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DIDO1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ERVEQFLTIA RRRGRRSMPV SLEDSGEPTS CPATDAETAS EGSVESASET
- Predicted Reactivity
- Cow: 92%, Dog: 92%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Yeast: 79%
- Characteristics
- This is a rabbit polyclonal antibody against DIDO1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human DIDO1
- Top Product
- Discover our top product DIDO1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 544 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- DIDO1 (Death Inducer-Obliterator 1 (DIDO1))
- Alternative Name
- DIDO1 (DIDO1 Products)
- Synonyms
- 5DI antibody, TXDI1 antibody, BYE1 antibody, C20orf158 antibody, DATF-1 antibody, DATF1 antibody, DIDO2 antibody, DIDO3 antibody, DIO-1 antibody, DIO1 antibody, dJ885L7.8 antibody, 6720461J16Rik antibody, C530043I07 antibody, D130048F08Rik antibody, Datf1 antibody, Dido2 antibody, Dido3 antibody, mKIAA0333 antibody, DIDO1 antibody, datf1l antibody, fi35b04 antibody, wu:fi35b04 antibody, zgc:158157 antibody, DKFZp469J1523 antibody, bye1 antibody, dio1 antibody, datf1 antibody, dido2 antibody, dido3 antibody, dio-1 antibody, iodothyronine deiodinase 1 antibody, death inducer-obliterator 1 antibody, death inducer-obliterator 1 L homeolog antibody, DIO1 antibody, DIDO1 antibody, Dido1 antibody, dido1.L antibody, dido1 antibody
- Background
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In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. DIDO1 gene is similar to the mouse gene and therefore is thought to be involved in apoptosis.Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.
Alias Symbols: BYE1, DIO1, DATF1, DIDO2, DIDO3, DIO-1, DATF-1, C20orf158, dJ885L7.8
Protein Interaction Partner: UBC, WWOX, RPA3, RPA2, RPA1, EED, BMI1, HECW2, SRPK2, KCNK4, ARAF, Dlg4, H2AFY, U2AF1, SON, RPL18A, KRT7, APP, PCDHA2, H2AFY2, GNL3, RRS1, SIRT7, SUMO2, WWP2, WWP1, DVL3, SRSF1, HNRNPK,
Protein Size: 544 - Molecular Weight
- 59 kDa
- Gene ID
- 11083
- NCBI Accession
- NM_080797, NP_542987
- Pathways
- Hormone Activity
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