MEIS2 antibody (N-Term)

Catalog No. ABIN2775951

Product Details anti-MEIS2 Antibody

Target: MEIS2 (Meis Homeobox 2 (MEIS2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Zebrafish (Danio rerio), Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MEIS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: HYGAHAPHPN VMPASMGSAV NDALKRDKDA IYGHPLFPLL ALVFEKCELA

Specificity: This antibody will recognize both MEIS1 and MEIS2 isoforms

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against MEIS2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MEIS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 477 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MEIS2 antibody (ABIN2775951)

Jackson, Brown, Avilion, OShaughnessy, Sully, Akinduro, Murphy, Cleary, Byrne: "TALE homeodomain proteins regulate site-specific terminal differentiation, LCE genes and epidermal barrier." in: Journal of cell science, Vol. 124, Issue Pt 10, pp. 1681-90, (2011) (PubMed).

Target Details for MEIS2

Target: MEIS2 (Meis Homeobox 2 (MEIS2))

Alternative Name: MEIS2 (MEIS2 Products)

Background: MEIS2 encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs.
Alias Symbols: MRG1, HsT18361
Protein Interaction Partner: LINC00238, C1orf94, OSGIN1, MEIS2, ANXA1, CRBN, ARNT2, DGCR6, SQSTM1, SOX2, APP, SP1, PBX1, ZNHIT3, TRIM25, HOXA13, HOXA9,
Protein Size: 477

Molecular Weight: 52 kDa

Gene ID: 4212

NCBI Accession: NM_170675, NP_733775

UniProt: O14770