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Angiomotin antibody (N-Term)

AMOT Reactivity: Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775937
  • Target See all Angiomotin (AMOT) Antibodies
    Angiomotin (AMOT)
    Binding Specificity
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 59
    • 13
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Human, Mouse, Rat, Horse, Dog, Guinea Pig, Rabbit, Cow, Zebrafish (Danio rerio)
    Host
    • 49
    • 10
    Rabbit
    Clonality
    • 53
    • 6
    Polyclonal
    Conjugate
    • 32
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiomotin antibody is un-conjugated
    Application
    • 38
    • 33
    • 14
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    TANKQLAEKE YEGSEDTRKT ISQLFAKNKE SQREKEKLEA ELATARSTNE
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
    Characteristics
    This is a rabbit polyclonal antibody against AMOT. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human AMOT
    Top Product
    Discover our top product AMOT Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 675 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Angiomotin (AMOT)
    Alternative Name
    AMOT (AMOT Products)
    Synonyms
    C81439 antibody, CAG-2 antibody, D0Kist1 antibody, E230009N18Rik antibody, Sii6 antibody, mKIAA1071 antibody, RGD1564027 antibody, si:dkey-13f9.6 antibody, wu:fj21a07 antibody, angiomotin antibody, microRNA 4329 antibody, AMOT antibody, Amot antibody, MIR4329 antibody, amot antibody
    Background
    AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
    Alias Symbols: KIAA1071
    Protein Interaction Partner: AMOT, C1orf216, WDYHV1, MED4, SNAPC5, PPP2R4, LURAP1, UNC119, LMO4, PIN1, MAGEA4, KRT31, KRT15, FUS, SEPT1, CEP76, HAUS2, LATS2, CEP250, CDKN1A, ACTB, ACTA1, YAP1, SART3, AURKB, MAPK3, BAG3, WWOX, ITCH, LATS1, YWHAG, UBC, PARK2, AMOTL1, SPICE1, MPP7, CNTR
    Protein Size: 675
    Molecular Weight
    73 kDa
    Gene ID
    154796
    NCBI Accession
    NM_133265, NP_573572
    UniProt
    Q4VCS5
    Pathways
    Cell-Cell Junction Organization, Regulation of Cell Size
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