PSIP1 antibody (Middle Region)

Catalog No. ABIN2775929

Product Details anti-PSIP1 Antibody

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Horse, Guinea Pig, Rabbit, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AADRKRKQEE QMETEQQNKD EGKKPEVKKV EKKRETSMDS RLQRIHAEIK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against PSIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PSIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1 (PSIP1 Products)

Background: PSIP1 is a transcriptional coactivator. It also acts as an adaptor to coordinate pre-mRNA splicing and transcriptional activation of class II genes.
Alias Symbols: p52, p75, PAIP, DFS70, LEDGF, PSIP2
Protein Interaction Partner: PPP2R1A, UBC, RPA3, RPA2, RPA1, HMGA2, HMGA1, WHSC1, CSNK2A1, gag-pol, ESR1, ZC3H18, FTSJ3, EXOSC5, EXOSC4, NCSTN, RRS1, SUPT16H, SAP18, THRAP3, EIF4A3, U2AF1, TPBG, SON, TRA2B, RPS24, RPS11, RPL6, CAST, SH3KBP1, MEN1, SUMO1, SUMO2, HDGF, MAPK6, KMT2A, BA
Protein Size: 530

Molecular Weight: 60 kDa

Gene ID: 11168

NCBI Accession: NM_033222, NP_150091

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization