METTL3 antibody (C-Term)

Catalog No. ABIN2775894

Product Details anti-METTL3 Antibody

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METTL3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KIELFGRPHN VQPNWITLGN QLDGIHLLDP DVVARFKQRY PDGIISKPKN

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against METTL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human METTL3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 580 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for METTL3

Target: METTL3 (Methyltransferase Like 3 (METTL3))

Alternative Name: METTL3 (METTL3 Products)

Synonyms: fj82g07 antibody, wu:fj82g07 antibody, zgc:77093 antibody, IME4 antibody, M6A antibody, MT-A70 antibody, Spo8 antibody, 2310024F18Rik antibody, methyltransferase like 3 antibody, methyltransferase like 3 L homeolog antibody, methyltransferase-like 3 antibody, mettl3 antibody, mettl3.L antibody, METTL3 antibody, Mettl3 antibody

Background: This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Alias Symbols: IME4, M6A, MGC4336, MT-A70, Spo8
Protein Interaction Partner: UBC, METTL14, UBD,
Protein Size: 580

Molecular Weight: 64 kDa

Gene ID: 56339

NCBI Accession: NM_019852, NP_062826

UniProt: Q86U44