HDAC8 antibody (N-Term)
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- Target See all HDAC8 Antibodies
- HDAC8 (Histone Deacetylase 8 (HDAC8))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC8 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MEEPEEPADS GQSLVPVYIY SPEYVSMCDS LAKIPKRASM VHSLIEAYAL
- Predicted Reactivity
- Cow: 86%, Dog: 86%, Guinea Pig: 91%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 79%
- Characteristics
- This is a rabbit polyclonal antibody against HDAC8. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HDAC8
- Top Product
- Discover our top product HDAC8 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 377 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HDAC8 (Histone Deacetylase 8 (HDAC8))
- Alternative Name
- HDAC8 (HDAC8 Products)
- Synonyms
- HD8 antibody, CDLS5 antibody, HDACL1 antibody, MRXS6 antibody, RPD3 antibody, WTS antibody, 2610007D20Rik antibody, RGD1562895 antibody, wu:fd19a02 antibody, zgc:66196 antibody, ATHDA8 antibody, HDA8 antibody, HISTONE DEACETYLASE 8 antibody, T27G7.14 antibody, T27G7_14 antibody, histone deacetylase 8 antibody, histone deacetylase 8 antibody, histone deacetylase 8 L homeolog antibody, CC1G_05302 antibody, hdac8 antibody, HDAC8 antibody, Hdac8 antibody, hdac8.L antibody, HDA08 antibody
- Background
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HDACL1, RPD3, HD8, CDA07
Protein Interaction Partner: MDM1, HDAC8, ZSCAN2, CHCHD3, STAG2, SEC16A, CROCC, SMC3, CPNE3, SMC1A, TPM4, TPM3, SVIL, NUP98, MME, ADD3, SMG5, SMG6, HSP90AA1, HSPA4, HIST4H4, HIST3H3, UBC, PRKACA, HIST1H4A, HIST1H3A, ESRRA, ACTA1, RTN1, PPP1CC, CREB1, HIST2H4A, RUNX1T1, CBFA2T3, MDC1,
Protein Size: 377 - Molecular Weight
- 42 kDa
- Gene ID
- 55869
- NCBI Accession
- NM_018486, NP_060956
- UniProt
- Q9BY41
- Pathways
- Cellular Glucan Metabolic Process
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