CAND1 antibody (N-Term)

Catalog No. ABIN2775888

Product Details anti-CAND1 Antibody

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAND1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TVIGELPPAS SGSALAANVC KKITGRLTSA IAKQEDVSVQ LEALDIMADM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TIP120A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TIP120A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CAND1

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Alternative Name: TIP120A (CAND1 Products)

Synonyms: TIP120 antibody, TIP120A antibody, ATCAND1 antibody, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 antibody, ETA2 antibody, HEMIVENATA antibody, HVE antibody, T8K22.14 antibody, T8K22_14 antibody, cullin-associated and neddylation dissociated antibody, Tip120 antibody, Tip120A antibody, fb78a05 antibody, wu:fb78a05 antibody, zgc:55729 antibody, tip120 antibody, tip120a antibody, cand2 antibody, 2310038O07Rik antibody, 6330512O03Rik antibody, AI195005 antibody, AI846556 antibody, D10Ertd516e antibody, Tp120a antibody, mKIAA0829 antibody, cullin associated and neddylation dissociated 1 antibody, cullin-associated and neddylation dissociated antibody, cullin-associated and neddylation-dissociated 1 antibody, cullin-associated and neddylation-dissociated 1 L homeolog antibody, cullin-associated NEDD8-dissociated protein 1 antibody, cullin associated and neddylation disassociated 1 antibody, CAND1 antibody, Cand1 antibody, cand1 antibody, cand1.L antibody, LOC100159824 antibody, LOC100177977 antibody

Background: TIP120A functions as a negative regulator of SCF E3 ubiquitin ligases and may modulate other cullin ligases in a similar fashion.
Alias Symbols: TIP120, TIP120A
Protein Interaction Partner: ISG15, SUMO2, SUMO3, UBE2D1, UBC, UBE2M, CUL1, ASB2, ASB1, PPM1G, PAWR, OSBP, KARS, GARS, CARS, APEH, STAT1, SHMT2, IPO7, SEC23A, JMJD6, HSPA4, TRMT112, ZYX, DCUN1D5, DCUN1D1, SRPK2, UBD, FBXL3, FN1, CFTR, vif, CA9, ECT2, NOTCH1, CUL4A, CUL5, RBX1, ERCC6,
Protein Size: 1230

Molecular Weight: 136 kDa

Gene ID: 55832

NCBI Accession: NM_018448, NP_060918

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization