SUV420H1 antibody (Middle Region)

Catalog No. ABIN2775877

Product Details anti-SUV420H1 Antibody

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUV420H1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: NNGFNSGSGS SSTKLKIQLK RDEENRGSYT EGLHENGVCC SDPLSLLESR

Predicted Reactivity: Dog: 86%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SUV420H1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUV420H1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 885 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SUV420H1 antibody (ABIN2775877)

Murata, Kondo, Sugimoto, Kawashima, Saito, Isomura, Kanda, Tsurumi: "Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells." in: Journal of virology, Vol. 86, Issue 9, pp. 4752-61, (2012) (PubMed).

Gatta, Mantovani: "NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations." in: Nucleic acids research, Vol. 36, Issue 20, pp. 6592-607, (2008) (PubMed).

Twells, Metzker, Brown, Cox, Garey, Hammond, Hey, Levy, Nakagawa, Philips, Todd, Hess: "The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13." in: Genomics, Vol. 72, Issue 3, pp. 231-42, (2001) (PubMed).

Target Details for SUV420H1

Target: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Alternative Name: SUV420H1 (SUV420H1 Products)

Synonyms: SUV420H1 antibody, wu:fb97g06 antibody, wu:fi57g03 antibody, zgc:103527 antibody, cgi-85 antibody, cgi85 antibody, kmt5b antibody, suv420h1 antibody, CGI85 antibody, KMT5B antibody, CGI-85 antibody, AA117471 antibody, C630029K18Rik antibody, Suv4-20h1 antibody, lysine methyltransferase 5B antibody, lysine methyltransferase 5B S homeolog antibody, KMT5B antibody, kmt5b antibody, kmt5b.S antibody, Kmt5b antibody

Background: SUV420H1 is a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined.
Alias Symbols: CGI-85, CGI85, KMT5B, MGC118906, MGC118909, MGC21161, MGC703
Protein Interaction Partner: SMARCD1, HIST1H4A, YWHAQ,
Protein Size: 885

Molecular Weight: 99 kDa

Gene ID: 51111

UniProt: Q4FZB7