LIMA1 antibody (Middle Region)
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- Target See all LIMA1 Antibodies
- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Horse, Cow, Dog, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LIMA1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GVLAASMEAK ASSQQEKEDK PAETKKLRIA WPPPTELGSS GSALEEGIKM
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 92%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against LIMA1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human LIMA1
- Top Product
- Discover our top product LIMA1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 759 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).
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EPLIN regulates actin dynamics by cross-linking and stabilizing filaments." in: The Journal of cell biology, Vol. 160, Issue 3, pp. 399-407, (2003) (PubMed).
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- Target
- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
- Alternative Name
- LIMA1 (LIMA1 Products)
- Synonyms
- eplin antibody, LIMA1 antibody, EPLIN antibody, MGC146397 antibody, SREBP3 antibody, 1110021C24Rik antibody, 3526402A12Rik antibody, D15Ertd366e antibody, Eplin antibody, LIM domain and actin binding 1 antibody, Lima1 antibody, LIMA1 antibody, lima1 antibody
- Background
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This gene encodes a cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles. It is downregulated in some cancer cell lines. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and expression of some of the variants maybe independently regulated.
Alias Symbols: EPLIN, SREBP3
Protein Interaction Partner: TP53, UBC, RPA3, RPA2, RPA1, SUZ12, RNF2, EZH2, BMI1, LRCH3, YWHAQ, YWHAB, PAN2, YWHAE, FMNL1, PAXIP1, ATP6V1B1, APP, UBXN6, LRRK2, ARRB2, ARRB1, SVIL, YWHAG,
Protein Size: 759 - Molecular Weight
- 85 kDa
- Gene ID
- 51474
- NCBI Accession
- NM_016357, NP_057441
- UniProt
- Q9UHB6
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