NRF1 antibody (Middle Region)
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- Target See all NRF1 Antibodies
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio), Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NRF1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- WATLQGGEMT IQTTQASEAT QAVASLAEAA VAASQEMQQG ATVTMALNSE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against NRF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human NRF1
- Top Product
- Discover our top product NRF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 503 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation." in: Mitochondrion, Vol. 13, Issue 6, pp. 637-46, (2013) (PubMed).
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Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation." in: Mitochondrion, Vol. 13, Issue 6, pp. 637-46, (2013) (PubMed).
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- Target
- NRF1 (Nuclear Respiratory Factor 1 (NRF1))
- Alternative Name
- NRF1 (NRF1 Products)
- Synonyms
- ALPHA-PAL antibody, C87038 antibody, D6Ertd415e antibody, SC:BZ3C13.1 antibody, SC:bZ3C13.2 antibody, ube2h antibody, Nfe2l1_retired antibody, IBR/F antibody, NRF1 antibody, alpha-pal antibody, nrf-1 antibody, LOC100220087 antibody, nuclear respiratory factor 1 antibody, nuclear respiratory factor 1 S homeolog antibody, NRF1 antibody, Nrf1 antibody, nrf1 antibody, nrf1.S antibody
- Background
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This protein homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth.
Alias Symbols: ALPHA-PAL
Protein Interaction Partner: POGZ, TRAF2, SP4, FHL2, DYNLL1, CSNK2B, CSNK2A1, UBC, HHV8GK18_gp81, CEBPB, PARP1, PPRC1, MAFF, PPARGC1A, Dynlt1b, CDK1, MRPL57, TFAM,
Protein Size: 503 - Molecular Weight
- 53 kDa
- Gene ID
- 4899
- NCBI Accession
- NM_005011, NP_005002
- UniProt
- Q16656
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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