HLTF antibody (N-Term)
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- Target See all HLTF Antibodies
- HLTF (Helicase-Like Transcription Factor (HLTF))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HLTF antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DPVWKYLQTV QYGVHGNFPR LSYPTFFPRF EFQDVIPPDD FLTSDEEVDS
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%
- Characteristics
- This is a rabbit polyclonal antibody against SMARCA3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCA3
- Top Product
- Discover our top product HLTF Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1009 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HLTF (Helicase-Like Transcription Factor (HLTF))
- Alternative Name
- SMARCA3 (HLTF Products)
- Synonyms
- smarca3 antibody, wu:fc33f07 antibody, HLTF antibody, SMARCA3 antibody, MGC131155 antibody, HIP116 antibody, HIP116A antibody, HLTF1 antibody, RNF80 antibody, SNF2L3 antibody, ZBU1 antibody, RUSH antibody, AF010600 antibody, BC057116 antibody, P113 antibody, Smarca3 antibody, Snf2l3 antibody, helicase like transcription factor antibody, helicase-like transcription factor antibody, helicase-like transcription factor L homeolog antibody, HLTF antibody, hltf antibody, hltf.L antibody, Hltf antibody
- Background
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SMARCA3 (HLTF) is a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA3 contains a RING finger DNA binding motif. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform which is truncated at the N-terminus as compared to the full-length protein.
Alias Symbols: ZBU1, HLTF1, RNF80, HIP116, SNF2L3, HIP116A, SMARCA3
Protein Interaction Partner: CHFR, UBC, RAD18, SUMO2, RPA3, RPA2, RPA1, WBP4, BRCA1, DTL, SULT1C2, HSPA8, CDK9, NOTCH1, SP3, SP1, SPRTN, Cebpb, ELAVL1, Shprh, RNF146, tat, EWSR1, UBE2Z, RPAP1, USP7, EEF1G, UBE2V2, UBE2N, PCNA,
Protein Size: 1009 - Molecular Weight
- 114 kDa
- Gene ID
- 6596
- NCBI Accession
- NM_139048, NP_620636
- UniProt
- Q14527
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