FHL2 antibody (C-Term)

Catalog No. ABIN2775839

Product Details anti-FHL2 Antibody

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FHL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RFTARDDFAY CLNCFCDLYA KKCAGCTNPI SGLGGTKYIS FEERQWHNDC

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 87%

Characteristics: This is a rabbit polyclonal antibody against FHL2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FHL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 279 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FHL2 antibody (ABIN2775839)

Han, Wu, Zhao, Meng, Si, Yang, Fu, Yu: "FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells." in: Nucleic acids research, Vol. 37, Issue 12, pp. 3996-4009, (2009) (PubMed).

Saeki, Endo, Ide, Nagashima, Yumoto, Toyoda, Suzuki, Hayashizaki, Sakaki, Okada-Hatakeyama: "Ligand-specific sequential regulation of transcription factors for differentiation of MCF-7 cells." in: BMC genomics, Vol. 10, pp. 545, (2009) (PubMed).

Lee, Chung, Kang: "Combined treatment of high pressure and heat on killing spores of Alicyclobacillus acidoterrestris in apple juice concentrate." in: Journal of food protection, Vol. 69, Issue 5, pp. 1056-60, (2006) (PubMed).

Target Details for FHL2

Target: FHL2 (Four and A Half LIM Domains 2 (FHL2))

Alternative Name: FHL2 (FHL2 Products)

Synonyms: AAG11 antibody, DRAL antibody, FHL-2 antibody, SLIM-3 antibody, SLIM3 antibody, C76204 antibody, FHL2 antibody, zgc:92428 antibody, zgc:103466 antibody, four and a half LIM domains 2 antibody, four and a half LIM domains 2a antibody, four and a half LIM domains 2b antibody, FHL2 antibody, Fhl2 antibody, fhl2 antibody, fhl2a antibody, fhl2b antibody

Background: FHL2 is a member of LIM proteins that contain a highly conserved double zinc finger motif called the LIM domain.
Alias Symbols: DRAL, AAG11, FHL-2, SLIM3, SLIM-3
Protein Interaction Partner: SP2, RFX3, REL, NRF1, JUP, INCA1, FAM154A, ZNF417, FAM129A, GLYR1, CCDC92, ARHGAP9, KIAA1217, GNG12, DCP1A, ZFP64, BANP, KANK2, RAI2, ZMYM4, BLZF1, ZNF131, CSN2, SIGLEC6, DTX2, TRIM63, TRIM55, FOXO1, SUMO2, PTCH1, DCTN3, HEXIM1, ERP44, SMAD4, SMAD3, SMAD2
Protein Size: 279

Molecular Weight: 32 kDa

Gene ID: 2274

NCBI Accession: NM_201555, NP_963849

UniProt: Q14192

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha