TRIM35 antibody (Middle Region)

Catalog No. ABIN2775798

Product Details anti-TRIM35 Antibody

Target: TRIM35 (Tripartite Motif Containing 35 (TRIM35))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM35 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ATKQLCKEFT DLLAQDRTPI GNSRPSPILE PGIQSCLTHF SLITHGFGAP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against TRIM35. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRIM35

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRIM35

Target: TRIM35 (Tripartite Motif Containing 35 (TRIM35))

Alternative Name: TRIM35 (TRIM35 Products)

Background: TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM35 may play a role as a tumor suppressor, and is implicated in the cell death mechanism. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this protein has not been identified.
Alias Symbols: HLS5, KIAA1098, MAIR, MGC17233
Protein Interaction Partner: USP49, PAN2, USP2, TRIM5, TRIM11, UBE2U, UBE2W, UBE2D4, UBE2D3, UBE2D2, UBE2D1, TSG101, UBE2K,
Protein Size: 493

Molecular Weight: 56 kDa

Gene ID: 23087

NCBI Accession: NM_171982, NP_741983

UniProt: Q9UPQ4