ARIH2 antibody (N-Term)

Catalog No. ABIN2775782

Product Details anti-ARIH2 Antibody

Target: ARIH2 (protein ariadne-2 homolog (ARIH2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARIH2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EDYDPNCEEE EEEEEDDPGD IEDYYVGVAS DVEQQGADAF DPEEYQFTCL

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARIH2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARIH2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 493 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARIH2

Target: ARIH2 (protein ariadne-2 homolog (ARIH2))

Alternative Name: ARIH2 (ARIH2 Products)

Synonyms: ARI2 antibody, TRIAD1 antibody, AI843547 antibody, UIP48 antibody, wu:fa09c12 antibody, zgc:64093 antibody, ariadne RBR E3 ubiquitin protein ligase 2 antibody, ariadne RBR E3 ubiquitin protein ligase 2 L homeolog antibody, ariadne homolog 2 (Drosophila) antibody, ARIH2 antibody, Arih2 antibody, arih2.L antibody, arih2 antibody

Background: ARIH2 might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2L3/UBCM4, and then transfers it to substrates.
Alias Symbols: ARI2, FLJ10938, FLJ33921, TRIAD1
Protein Interaction Partner: UBE2L3, UBC, REL, MDM2, CCDC33, UBE2L6, PABPN1, UGP2, APEX1, PARP6, TWF2, EHD1, PDLIM1, PAPSS2, NUBP1, HK2, ARIH2, CUL5, NEDD8, RHEB, VCP, NOTCH1, PHF7, TRIM27, UBE2N, TP53, PML, DISC1, UBE2R2, UBE2D4, UBE2T, UBE2E3, UBE2V1, UBE2E2, UBE2E1, UBE2D3, UBE2D2
Protein Size: 493

Molecular Weight: 58 kDa

Gene ID: 10425

NCBI Accession: NM_006321, NP_006312

UniProt: O95376