CIAO1 antibody (C-Term)

Catalog No. ABIN2775775

Product Details anti-CIAO1 Antibody

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIAO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LSGFHSRTIY DIAWCQLTGA LATACGDDAI RVFQEDPNSD PQQPTFSLTA

Predicted Reactivity: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against WDR39. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDR39

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 339 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CIAO1

Target: CIAO1 (Cytosolic Iron-Sulfur Protein Assembly 1 (CIAO1))

Alternative Name: WDR39 (CIAO1 Products)

Synonyms: CG12797 antibody, Dmel\\CG12797 antibody, DDBDRAFT_0190506 antibody, DDBDRAFT_0266672 antibody, DDB_0190506 antibody, DDB_0266672 antibody, CIA1 antibody, WDR39 antibody, AW210570 antibody, Wdr39 antibody, wdr39 antibody, zgc:55911 antibody, zgc:77394 antibody, CG12797 gene product from transcript CG12797-RA antibody, WD40 protein Ciao1 antibody, CIAO1 antibody, WD40 repeat-containing protein antibody, cytosolic iron-sulfur assembly component 1 antibody, cytosolic iron-sulfur protein assembly 1 antibody, Ciao1 antibody, cgd1_2230 antibody, CC1G_05316 antibody, ciao1 antibody, CIAO1 antibody

Background: WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Alias Symbols: CIAO1, CIA1, WDR39
Protein Interaction Partner: FAM96B, SF1, MEOX1, FAM96A, MMS19, FMNL2, TOE1, DPP9, FMNL3, CTU1, PPIL4, MAK16, WDR75, NSRP1, EEPD1, WDR61, CDC73, UPF3B, NARFL, YAE1D1, TYW1, ELP2, ELP3, UCKL1, CDKAL1, DPP8, ELP6, PAF1, PLEKHA5, PHAX, RTEL1, ELP4, POLA2, ELP5, WDR43, ERP29, GLRX3, CTR9
Protein Size: 339

Molecular Weight: 38 kDa

Gene ID: 9391

NCBI Accession: NM_004804, NP_004795

UniProt: O76071