CRIP2 antibody (N-Term)

Catalog No. ABIN2775755

Product Details anti-CRIP2 Antibody

Target: CRIP2 (Cysteine-Rich Protein 2 (CRIP2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKPLAEGPQV TGPIEVPAAR AEERKASGPP KGPSRASSVT TFTGEPNTCP

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CRIP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CRIP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 208 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CRIP2 antibody (ABIN2775755)

Tsui, Chan, Cheuk, Liew, Waye, Fung, Lee: "A novel cDNA encoding for a LIM domain protein located at human chromosome 14q32 as a candidate for leukemic translocation." in: Biochemistry and molecular biology international, Vol. 39, Issue 4, pp. 747-54, (1997) (PubMed).

Target Details for CRIP2

Target: CRIP2 (Cysteine-Rich Protein 2 (CRIP2))

Alternative Name: CRIP2 (CRIP2 Products)

Background: Human ESP1/CRP2 protein has two LIM domains, and each shares 35.1 % and 77 or 79 % identical residues with human cysteine-rich protein (CRP) and rat CRIP, respectively. Northern blot analysis of ESP1/CRP2 in various human tissues showed distinct tissue distributions compared with CRP and CRIP, suggesting that each might serve related but specific roles in tissue organization or function. Using a panel of human-rodent somatic cell hybrids, the ESP1/CRP2 locus was assigned to chromosome 14. Fluorescence in situ hybridization, using cDNA and a genome DNA fragment of the ESP1/CRP2 as probes, confirms this assignment and relegates regional localization to band 14q32.3.
Alias Symbols: CRIP, CRP2, ESP1
Protein Interaction Partner: BAG3, ATXN1, APP, ATN1, OSGEP, GADD45G, SPRY2, TK1, KLF10, SMN1, PCYT2, ATP1B1, GATA6, GATA4, PRKG1, SRF, PTPN13,
Protein Size: 208

Molecular Weight: 22 kDa

Gene ID: 1397

NCBI Accession: NM_001312, NP_001303

UniProt: P52943