CHD4 antibody (N-Term)
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- Target See all CHD4 Antibodies
- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHD4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- QKKERMLLCR QLGDSSGEGP EFVEEEEEVA LRSDSEGSDY TPGKKKKKKL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against CHD4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CHD4
- Top Product
- Discover our top product CHD4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 1912 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CHD4 (Chromodomain Helicase DNA Binding Protein 4 (CHD4))
- Alternative Name
- CHD4 (CHD4 Products)
- Synonyms
- CHD4 antibody, im:7143343 antibody, si:ch211-51m24.3 antibody, si:ch211-57k11.10 antibody, wu:fb44b12 antibody, wu:fd12d03 antibody, MGC145363 antibody, Mi-2b antibody, Mi2-BETA antibody, Mi-2 antibody, 9530019N15Rik antibody, AA617397 antibody, BC005710 antibody, D6Ertd380e antibody, Mi-2beta antibody, mKIAA4075 antibody, b230399n07 antibody, chromodomain helicase DNA binding protein 4 antibody, chromodomain helicase DNA binding protein 4a antibody, chromodomain helicase DNA binding protein 4b antibody, chromodomain helicase DNA binding protein 4 L homeolog antibody, CHD4 antibody, chd4a antibody, chd4b antibody, chd4 antibody, Chd4 antibody, chd4.L antibody
- Background
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CHD4 is a probable transcription regulator.The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp686E06161, Mi-2b, Mi2-BETA
Protein Interaction Partner: SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, UBC, LGR4, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, BMI1, GATAD2A, HDAC2, HDAC1, MTA3, CSNK2A1, HIST3H3, VCAM1, ITGA4, NOTCH1, ESR1, TBL1XR1, MBD3, MTA2, SMARCC1, RBBP7, RBBP4, CHD3, SNAI1, SNAI2, SUMO1, NEDD8, MTA1, NR2C2,
Protein Size: 1912 - Molecular Weight
- 218 kDa
- Gene ID
- 1108
- NCBI Accession
- NM_001273, NP_001264
- UniProt
- Q14839
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