NCS1 antibody (N-Term)

Catalog No. ABIN2775722

Product Details anti-NCS1 Antibody

Target: NCS1 (Neuronal Calcium Sensor 1 (NCS1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Zebrafish (Danio rerio), Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MGKSNSKLKP EVVEELTRKT YFTEKEVQQW YKGFIKDCPS GQLDAAGFQK

Predicted Reactivity: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against FREQ. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FREQ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 190 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NCS1 antibody (ABIN2775722)

OCallaghan, Burgoyne: "Identification of residues that determine the absence of a Ca(2+)/myristoyl switch in neuronal calcium sensor-1." in: The Journal of biological chemistry, Vol. 279, Issue 14, pp. 14347-54, (2004) (PubMed).

Target Details for NCS1

Target: NCS1 (Neuronal Calcium Sensor 1 (NCS1))

Alternative Name: FREQ (NCS1 Products)

Synonyms: FREQ antibody, NCS-1 antibody, LOC100189965 antibody, FLUP antibody, freq antibody, freqa antibody, zgc:63620 antibody, 9430075O15Rik antibody, A730032G13Rik antibody, AI836659 antibody, Freq antibody, Mfreq antibody, flup antibody, xfreq antibody, MGC75953 antibody, freqb antibody, wu:fa55b03 antibody, neuronal calcium sensor 1 antibody, neuronal calcium sensor 1a antibody, frequenin homolog antibody, neuronal calcium sensor 1 L homeolog antibody, calcium sensor-1 antibody, calcium-binding protein NCS-1 antibody, Neuronal calcium sensor 1 antibody, neuronal calcium sensor 1b antibody, NCS1 antibody, ncs1a antibody, freq antibody, Ncs1 antibody, ncs1 antibody, ncs1.L antibody, cse-1 antibody, MGYG_03475 antibody, PGTG_09250 antibody, Tsp_06748 antibody, ncs-1 antibody, ncs1b antibody

Background: FREQ is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. This protein is thought to be associated with secretory granules and may be involved in the regulation of neurosecretion.
Alias Symbols: FLUP, FREQ
Protein Interaction Partner: NBL1, DTX2, NAF1, KIF21A, KDM3B, SRP68, SNRPB, UBC, ELAVL1, PI4KB, KCND2, IL1RAPL1, DRD5, DRD3, DRD2, ADRBK1,
Protein Size: 190

Molecular Weight: 22 kDa

Gene ID: 23413

NCBI Accession: NM_014286, NP_055101

UniProt: P62166