FKBP6 antibody (Middle Region)

Catalog No. ABIN2775685

Product Details anti-FKBP6 Antibody

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FKBP6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FKBP6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 467 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP6

Target: FKBP6 (FK506 Binding Protein 6, 36kDa (FKBP6))

Alternative Name: FKBP6 (FKBP6 Products)

Synonyms: 1700008G22Rik antibody, 36kDa antibody, AU017274 antibody, D5Ertd724e antibody, FKBP-36 antibody, FKBP-6 antibody, PPiase antibody, FKBP36 antibody, FK506 binding protein 6 antibody, FK506 binding protein 6 L homeolog antibody, Fkbp6 antibody, fkbp6.L antibody, FKBP6 antibody

Background: FKBP6 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP6 is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin.This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
Alias Symbols: FKBP36, MGC87179, PPIase
Protein Interaction Partner: LZTS2, CDK5RAP3, SUMO1P1, CCDC36, CDC37, USP19, PTGES3, VBP1, PFDN2, OSBP, HSP90AB1, HSP90AA1, TINF2, ACD, NME7, CCNK, GAPDH,
Protein Size: 467

Molecular Weight: 53 kDa

Gene ID: 8468

NCBI Accession: NM_006147, NP_003593

UniProt: O75344

Pathways: M Phase