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UBE2D3 antibody (N-Term)

UBE2D3 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775674
  • Target See all UBE2D3 Antibodies
    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
    Binding Specificity
    • 8
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)
    Host
    • 33
    • 1
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2D3 antibody is un-conjugated
    Application
    • 23
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against UBE2D3. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D3
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 147 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
    Alternative Name
    UBE2D3 (UBE2D3 Products)
    Synonyms
    E2(17)KB3 antibody, UBC4/5 antibody, UBCH5C antibody, eff antibody, fb36f02 antibody, wu:fb36f02 antibody, zgc:56340 antibody, 1100001F19Rik antibody, 9430029A22Rik antibody, AA414951 antibody, UBE2D3P antibody, Xubc4 antibody, e2(17)kb3 antibody, ubc4/5 antibody, ubch5c antibody, ube2d3.1 antibody, ube2d2 antibody, xubc4 antibody, wu:fj13d01 antibody, zgc:73200 antibody, ubiquitin conjugating enzyme E2 D3 antibody, ubiquitin-conjugating enzyme E2D 3 antibody, ubiquitin conjugating enzyme E2 D3 L homeolog antibody, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like antibody, UBE2D3 antibody, ube2d3 antibody, Ube2d3 antibody, LOC100223566 antibody, ube2d3.L antibody, ube2d2l antibody
    Background
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
    Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
    Protein Interaction Partner: NHLRC1, DTX2, TRIM63, RNF146, RNF26, RBX1, UBC, RNF5, RNF2, NEDD4, MID1, STUB1, TRIM39, OTUB1, MDM2, RNF111, TRIM33, PRPF19, RNF115, TRIM58, BTRC, MARCH7, NFKBIA, ARIH1, FBXW11, UBE2D3, PARK2, BRCA1, BARD1, UBE3A, MSL1, UBA1, CBLC, SMURF1, RNF130, UBA6, M
    Protein Size: 147
    Molecular Weight
    17 kDa
    Gene ID
    7323
    NCBI Accession
    NM_003340, NP_003331
    UniProt
    P61077
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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