PEX10 antibody (C-Term)

Catalog No. ABIN2775670

Product Details anti-PEX10 Antibody

Target: PEX10 (Peroxisomal Biogenesis Factor 10 (PEX10))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ERRHPTATPC GHLFCWECIT AWCSSKAECP LCREKFPPQK LIYLRHYR

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PEX10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PEX10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEX10

Target: PEX10 (Peroxisomal Biogenesis Factor 10 (PEX10))

Alternative Name: PEX10 (PEX10 Products)

Background: PEX10 is a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in PEX10 gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome.This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: MGC1998, NALD, RNF69
Protein Interaction Partner: HNRNPD, PEX5, PEX14, LIG4, PCGF6, CGRRF1, MKRN3, PEX19, PEX12, PEX10, UBC, UBE2I, PEX2,
Protein Size: 326

Molecular Weight: 37 kDa

Gene ID: 5192

NCBI Accession: NM_002617, NP_002608

UniProt: O60683

Pathways: Monocarboxylic Acid Catabolic Process