TJP2 antibody (Middle Region)

Catalog No. ABIN2775642

Product Details anti-TJP2 Antibody

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TJP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TVVPETNKEP RYQEDPPAPQ PKAAPRTFLR PSPEDEAIYG PNTKMVRFKK

Predicted Reactivity: Dog: 100%, Horse: 92%, Human: 100%, Rabbit: 93%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against TJP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TJP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1190 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TJP2

Target: TJP2 (Tight Junction Protein 2 (Zona Occludens 2) (TJP2))

Alternative Name: TJP2 (TJP2 Products)

Synonyms: C9DUPq21.11 antibody, DFNA51 antibody, DUP9q21.11 antibody, X104 antibody, ZO2 antibody, ZO-2 antibody, zo2 antibody, tjp2 antibody, x104 antibody, zo-2 antibody, wu:fb62b09 antibody, zgc:92094 antibody, tight junction protein 2 antibody, tight junction protein 2 L homeolog antibody, tight junction protein 2b (zona occludens 2) antibody, TJP2 antibody, Tjp2 antibody, tjp2.L antibody, tjp2b antibody

Background: Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions. TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1975 BC027592.1 10-1984 1976-2543 L27476.1 1855-2422 2544-3080 BC028426.1 2440-2976 3081-4167 BC027592.1 3090-4176 4168-4601 L27476.1 4051-4484 4602-4618 BC028426.1 4056-4072
Alias Symbols: MGC26306, X104, ZO-2, ZO2, DFNA51, DUP9q21.11, C9DUPq21.11
Protein Interaction Partner: SNAI2, UBC, KCMF1, PGAM5, KIAA1671, LATS2, YAP1, KIF14, LATS1, TJP1, SRPK2, SRPK1, PLOD1, CDK6, ZMYM3, THOC5, UBN1, CLDN2, SIRT7, SSTR3, YWHAZ, YWHAG, YWHAB, OCLN, SRRM2, KBTBD7, RAE1, CGN, SCRIB, CLDN1, SAFB, SH3KBP1, EPB41, CTNNA1, HGS, YWHAQ, TRAF6, SF
Protein Size: 1190

Molecular Weight: 134 kDa

Gene ID: 9414

NCBI Accession: NM_004817, NP_004808

UniProt: Q9UDY2