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AMOTL1 antibody (N-Term)

AMOTL1 Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775636
  • Target See all AMOTL1 Antibodies
    AMOTL1 (Angiomotin Like 1 (AMOTL1))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 32
    • 16
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Cow, Dog, Guinea Pig, Rabbit
    Host
    • 28
    • 4
    Rabbit
    Clonality
    • 30
    • 2
    Polyclonal
    Conjugate
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This AMOTL1 antibody is un-conjugated
    Application
    • 14
    • 11
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LTQEDPQMVY QSARQEPQGQ EHQVDNTVME KQVRSTQPQQ NNEELPTYEE
    Predicted Reactivity
    Cow: 93%, Dog: 79%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%
    Characteristics
    This is a rabbit polyclonal antibody against AMOTL1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human AMOTL1
    Top Product
    Discover our top product AMOTL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 956 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Skouloudaki, Walz: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).

    Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

  • Target
    AMOTL1 (Angiomotin Like 1 (AMOTL1))
    Alternative Name
    AMOTL1 (AMOTL1 Products)
    Synonyms
    JEAP antibody, 2310010G08Rik antibody, 2310067L22Rik antibody, 4932416D09Rik antibody, mFLJ00155 antibody, angiomotin like 1 antibody, angiomotin-like 1 antibody, AMOTL1 antibody, Amotl1 antibody
    Background
    AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
    Alias Symbols: JEAP
    Protein Interaction Partner: WWOX, SUZ12, NEDD4, HECW2, AMOT, LATS2, YAP1, LATS1, Wwtr1, UBC, Magi1, NEDD4L,
    Protein Size: 956
    Molecular Weight
    106 kDa
    Gene ID
    154810
    NCBI Accession
    NM_130847, NP_570899
    UniProt
    Q8IY63
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