MPDZ antibody (Middle Region)

Catalog No. ABIN2775622

Product Details anti-MPDZ Antibody

Target: MPDZ (Multiple PDZ Domain Protein (MPDZ))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPDZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DEAINVLRQT PQRVRLTLYR DEAPYKEEEV CDTLTIELQK KPGKGLGLSI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MPDZ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MPDZ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 2041 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MPDZ antibody (ABIN2775622)

Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

Target Details for MPDZ

Target: MPDZ (Multiple PDZ Domain Protein (MPDZ))

Alternative Name: MPDZ (MPDZ Products)

Background: The exact function of MPDZ remains unknown.
Alias Symbols: DKFZp781P216, FLJ25909, FLJ34626, FLJ90240, MUPP1
Protein Interaction Partner: WWOX, AMOT, AMOTL2, LATS2, YAP1, Wwtr1, UBC, SSTR3, SYNGAP1, F11R, PLEKHA1, MPDZ, CAMK2A, CLDN1, RNF5, CLDN5, CSPG4, ABCA1, HTR2C, KIT, DRD3, PLEKHA2,
Protein Size: 2041

Molecular Weight: 218 kDa

Gene ID: 8777

NCBI Accession: NM_003829, NP_003820

UniProt: O75970

Pathways: Synaptic Membrane, Phototransduction