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PARD6A antibody (N-Term)

PARD6A Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Guinea Pig, Dog WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775615
  • Target See all PARD6A Antibodies
    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
    Binding Specificity
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 24
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Horse, Guinea Pig, Dog
    Host
    • 24
    • 2
    • 1
    Rabbit
    Clonality
    • 27
    Polyclonal
    Conjugate
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARD6A antibody is un-conjugated
    Application
    • 15
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PARD6A. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A
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    Discover our top product PARD6A Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 345 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))
    Alternative Name
    PARD6A (PARD6A Products)
    Synonyms
    PARD6A antibody, 0710008C04Rik antibody, 2610010A15Rik antibody, PAR6alpha antibody, Par-6 antibody, Par6 antibody, Par6c antibody, TAX40 antibody, Tip-40 antibody, Par-6a antibody, Par6a antibody, PAR-6A antibody, PAR6 antibody, PAR6C antibody, TIP-40 antibody, par-6 partitioning defective 6 homolog alpha (C. elegans) antibody, par-6 family cell polarity regulator alpha antibody, Partitioning defective protein 6 antibody, PARD6A antibody, Pard6a antibody, par-6 antibody
    Background
    This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
    Protein Interaction Partner: PRKCI, WDR83, PRKCZ, FBXO31, PARD3, UBC, TUBG1, ARHGAP17, VHL, MAP2K5, TJP1, SMURF1, TGFB1, WDR92, PARD6B, PDRG1, RPAP3, MARK4, PIH1D1, SUGT1, YWHAZ, YWHAH, LLGL1, LLGL2, MARK2, CDC42, CRB3, ECT2, PLCB1, RHOQ, PRKCH, RAC1, CDH5, PLCB3, TGFBR1, TCP10, PRKC
    Protein Size: 345
    Molecular Weight
    37 kDa
    Gene ID
    50855
    NCBI Accession
    NM_001037281, NP_001032358
    UniProt
    Q3TY70
    Pathways
    Cell-Cell Junction Organization
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