PANX1 antibody (Middle Region)

Catalog No. ABIN2775573

Product Details anti-PANX1 Antibody

Target: PANX1 (Pannexin 1 (PANX1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PANX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LGYYFSLSSL SDEFVCSIKS GILRNDSTVP DQFQCKLIAV GIFQLLSVIN

Predicted Reactivity: Cow: 92%, Dog: 83%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 77%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PANX1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PANX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 426 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PANX1

Target: PANX1 (Pannexin 1 (PANX1))

Alternative Name: PANX1 (PANX1 Products)

Synonyms: panx1 antibody, zgc:55631 antibody, PANX1 antibody, px1 antibody, mrs1 antibody, pannexin1 antibody, Pannexin-1 antibody, MRS1 antibody, PX1 antibody, UNQ2529 antibody, AI847747 antibody, pannexin 1a antibody, pannexin 1 antibody, Pannexin 1 antibody, panx1a antibody, PANX1 antibody, panx1 antibody, Panx1 antibody

Background: PANX1 belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
Alias Symbols: MGC21309, MRS1, UNQ2529, PX1
Protein Interaction Partner: GNAS, UBC, P2RX7,
Protein Size: 426

Molecular Weight: 47 kDa

Gene ID: 24145

NCBI Accession: NM_015368, NP_056183

UniProt: Q96RD7