GAMT antibody (Middle Region)

Catalog No. ABIN502292

Product Details anti-GAMT Antibody

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAMT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PGEGPFLTPW VGWTVLVHLE IKVLCLAQWL PGAVAQVYNP STVEGRGGQI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against GAMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GAMT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 269 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GAMT antibody (ABIN502292)

Borini, Staiano, Rocchia, Rossi, Rossi, DAuria: "Advanced nanotechnological approaches for designing protein-based "lab-on-chips" sensors on porous silicon wafer." in: Recent patents on DNA & gene sequences, Vol. 1, Issue 1, pp. 1-7, (2008) (PubMed).

Target Details for GAMT

Target: GAMT (Guanidinoacetate N-Methyltransferase (GAMT))

Alternative Name: GAMT (GAMT Products)

Background: GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in its gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumula
Alias Symbols: PIG2, TP53I2
Protein Interaction Partner: FOS, CSNK2B, UBC, TERF2IP, POT1, TERF1,
Protein Size: 269

Molecular Weight: 29 kDa

Gene ID: 2593

NCBI Accession: NM_138924, NP_620279

UniProt: A8K0A0