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DNASE2B antibody (N-Term)

DNASE2B Reactivity: Human, Guinea Pig, Cow, Horse, Rat, Dog, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2775490
  • Target See all DNASE2B Antibodies
    DNASE2B (Deoxyribonuclease II beta (DNASE2B))
    Binding Specificity
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 16
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Human, Guinea Pig, Cow, Horse, Rat, Dog, Rabbit
    Host
    • 15
    • 1
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    This DNASE2B antibody is un-conjugated
    Application
    • 13
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    EGKAVDWFTF YKLPKRQNKE SGETGLEYLY LDSTTRSWRK SEQLMNDTKS
    Predicted Reactivity
    Cow: 79%, Dog: 82%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Rabbit: 86%, Rat: 86%
    Characteristics
    This is a rabbit polyclonal antibody against DNASE2B. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human DNASE2B
    Top Product
    Discover our top product DNASE2B Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 357 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DNASE2B (Deoxyribonuclease II beta (DNASE2B))
    Alternative Name
    DNASE2B (DNASE2B Products)
    Synonyms
    DNASE2 antibody, deoxyribonuclease-2-beta antibody, DLAD antibody, DNASE2B antibody, dnase2b antibody, AI526873 antibody, Dlad antibody, DnaseIIb antibody, UOX antibody, deoxyribonuclease 2 beta antibody, deoxyribonuclease II beta antibody, DNASE2B antibody, dnase2b antibody, Dnase2b antibody
    Background
    DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: DLAD
    Protein Interaction Partner: UBC, UBD,
    Protein Size: 357
    Molecular Weight
    39 kDa
    Gene ID
    58511
    NCBI Accession
    NM_021233, NP_067056
    UniProt
    Q8WZ79
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