RHCE antibody (N-Term)

Catalog No. ABIN2775479

Product Details anti-RHCE Antibody

Target: RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHCE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SSKYPRSVRR CLPLCALTLE AALILLFYFF THYDASLEDQ KGLVASYQVG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RHCE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RHCE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 266 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RHCE antibody (ABIN2775479)

McMahon, Okeeffe, , Grayson: "Is hospital-in-the-home (HITH) treatment of bacterial endocarditis safe and effective?" in: Scandinavian journal of infectious diseases, Vol. 40, Issue 1, pp. 40-3, (2007) (PubMed).

Target Details for RHCE

Target: RHCE (Rhesus Blood Group, CcEe Antigens (RHCE))

Alternative Name: RHCE (RHCE Products)

Synonyms: CD240CE antibody, RH antibody, RH30A antibody, RHC antibody, RHE antibody, RHIXB antibody, RHPI antibody, Rh4 antibody, RhIVb(J) antibody, RhVI antibody, RhVIII antibody, RHCE antibody, Rh blood group CcEe antigens antibody, Rh blood group, CcEe antigens antibody, RHCE antibody

Background: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease.The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in four transcript variants encoding four different isoforms.
Alias Symbols: CD240CE, MGC103977, RH, RH30A, RHC, RHE, RHIXB, RHPI, Rh4, RhIVb(J), RhVI, RhVIII
Protein Size: 266

Molecular Weight: 29 kDa

Gene ID: 6006

NCBI Accession: NM_138616, NP_619522

UniProt: P18577