HAO1 antibody (C-Term)

Catalog No. ABIN2775438

Product Details anti-HAO1 Antibody

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Cow, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAO1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLNGILVSNH GARQLDGVPA TIDVLPEIVE AVEGKVEVFL DGGVRKGTDV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against HAO1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HAO1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 370 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HAO1 antibody (ABIN2775438)

Williams, Cregeen, Rumsby: "Identification and expression of a cDNA for human glycolate oxidase." in: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 246-8, (2000) (PubMed).

Target Details for HAO1

Target: HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))

Alternative Name: HAO1 (HAO1 Products)

Synonyms: hao1 antibody, GOX antibody, GOX1 antibody, HAOX1 antibody, Gox1 antibody, XDH1 antibody, Hao-1 antibody, hydroxyacid oxidase 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 antibody, hydroxyacid oxidase (glycolate oxidase) 1 L homeolog antibody, hydroxyacid oxidase 1, liver antibody, CpipJ_CPIJ013711 antibody, THEYE_A0075 antibody, hao1 antibody, HAO1 antibody, hao1.L antibody, Hao1 antibody

Background: Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
Alias Symbols: GOX, GOX1, HAOX1
Protein Interaction Partner: PEX5, HCVgp1,
Protein Size: 370

Molecular Weight: 41 kDa

Gene ID: 54363

NCBI Accession: NM_017545, NP_060015

UniProt: Q9UJM8

Pathways: Monocarboxylic Acid Catabolic Process