CRNN antibody (Middle Region)

Catalog No. ABIN2775428

Product Details anti-CRNN Antibody

Target: CRNN (Cornulin (CRNN))

Binding Specificity: Middle Region

Reactivity: Human, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRNN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GDRQPTVVGE EWVDDHSRET VILRLDQGNL HTSVSSAQGQ DAAQSEEKRG

Predicted Reactivity: Dog: 85%, Horse: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CRNN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRNN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 481 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRNN

Target: CRNN (Cornulin (CRNN))

Alternative Name: CRNN (CRNN Products)

Background: This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
Alias Symbols: C1orf10, PDRC1, SEP53, DRC1
Protein Interaction Partner: WWOX, ZBTB1,
Protein Size: 481

Molecular Weight: 52 kDa

Gene ID: 49860

NCBI Accession: NM_016190, NP_057274

UniProt: Q9UBG3